Liver disease (Liver) and its Relationship With Basil Leaves

Liver disease (Liver) and its Relationship With Basil Leaves

Liver disease (Liver) and its Relationship With Basil Leaves -- Liver disease or liver disease often referred to (in the true sense) is one of the degenerative metabolic disease remains a global health problem. World Health Organization (WHO) says about a third of the world population, or about 2 trillion people suffering from liver disease with mortality rates reaching 1 million as reported by Reuters in 2011. However the reality treatment of liver disease progression is still often cause unwanted side effects.

Liver disorders besides can be be caused by infection microorganisms, diseases descent and metabolic, drug, toxin, and other causes. Various drugs and food can as a substance which toxic and cause cell damage liver. Liver disorders by because of these drugs usually constitute direct toxic which dependent on the of each individual (Akbar, 2007).

One of one drug which can cause the abnormalities the liver is acetaminophen or paracetamol, constitute analgesic drugs-antipyretic who known widely in society and known as a medicine freely or Over Reviews the Counter Drug (OTC) and can be be obtained easy in store drug nor the pharmacies without a prescription doctor's. Because easy it is obtained, risk for the occurrence of misuse paracetamol become more big.

Liver damage a result of paracetamol caused by process oxidative stress metabolic NAPQI which very reactive it were covalently bonded with macromolecules vital liver cell. Damage who arise in the form necrosis sentrilobularis (Wilmana and Gan, 2007). Enzymes who relate with liver damage namely aminotransferase and oxidoreductase. Serum Glutamate Pyruvate transaminase (SGPT) is enzyme aminotransferase who are normally present in tissues body especially in the liver. SGPT levels in the blood will rise in liver damage caused by paracetamol.

Consumption of foods rich in antioxidants can reduce diseases caused by oxidative stress and inflammation. Antioxidants also play an important role in inhibiting and neutralizing free radicals as it has been presented by Rajkapoor et al., 2008. In addition, antioxidants can block the oxidative process and neutralize free radicals to prevent a variety of degenerative diseases in the human body.

Of various types of herbs that are known to contain antioxidants, silymarin is a herbal remedy that has protective and curative effects against hepatic. Milk thistle has been used since used to treat liver disease. Hepatoprotektornya effect has been known since hundreds of years ago.

Besides silymarin, which attracted the attention of authors is Ocimum sanctum or commonly known as the basil leaves. Basil leaves commonly consumed vegetables Indonesia as supplementary material in a variety of food stalls. In addition, because it smells fragrant, basil is more often used for hand washing. Antioxidant compounds contained in the form of Ocimum sanctum phenolic compounds (tocopherols, flavonoids, phenolic acids), nitrogen compounds (alkaloids, chlorophyll derivatives, amino acids, and amines), and beta carotene.

So from the description above is possible leaf basil has countless benefits for the health of the body. Including for the treatment of degenerative diseases such as liver and his other on the human body.